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Targets Recommended: VEGFR

54

抑制剂 & 化合物

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化合物库

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Cat. No. Product Name
L2193 抗肝癌化合物库

1787 compounds
1787 种与肝癌相关的化合物,可以用于抗肝癌药物研发和药理研究;

化合物库

抗肝癌化合物库
Cat.No: L2193
Compounds: 1787
Cat. No. Product Name Target Signaling Pathways
T4288 hVEGF-IN-1

VEGFR Angiogenesis; Tyrosine Kinase/Adaptors
hVEGF-IN-1 是一种喹唑啉衍生物,可以特异性结合内部核糖体进入位点 A 中富含 G 的序列,并会使 G-四链体结构不稳定。在 SPR 实验中,它与 IRES-A (WT) 结合的Kd 值为 0.928 μM。它能够抑制VEGF-A 蛋白表达,阻止肿瘤细胞迁移,抑制肿瘤生长。
T21445 Naphazoline

AK-Con,Naphcon-a,Clear Eyes,All Clear,萘甲唑林

Adrenergic Receptor GPCR/G Protein; Neuroscience
Naphazoline (Naphcon-a) 是一种具有显着 α 肾上腺素能活性的拟交感神经化合物。 萘甲唑啉可用作血管收缩剂,当应用于粘膜时可快速减少肿胀。
T2479 Tyrphostin A9

Malonoben,Tyrphostin 9,SF 6847,AG 17,RG-50872

EGFR; VEGFR; Influenza Virus; PDGFR Angiogenesis; JAK/STAT signaling; Microbiology/Virology; Tyrosine Kinase/Adaptors
Tyrphostin A9 (SF 6847) 是一种线粒体分裂诱导剂,是 PDGFR 抑制剂,具有抗流感病毒的活性。
T5475 ZD-4190

EGFR; VEGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
ZD-4190 是血管内皮细胞生长因子受体 2 (VEGFR2) 和表皮生长因子受体 (EGFR) 信号传导的抑制剂,用于治疗癌症。
T22432 SU5208

3-[(Thien-2-yl)methylene]-2-indolinone

VEGFR Angiogenesis; Tyrosine Kinase/Adaptors
SU5208 (3-[(Thien-2-yl)methylene]-2-indolinone) 对血管内皮生长因子受体2具有抑制作用。
T3641 NVP-BAW2881

BAW2881

Raf; VEGFR; Bcr-Abl Angiogenesis; Cytoskeletal Signaling; MAPK; Tyrosine Kinase/Adaptors
NVP-BAW2881 (BAW2881) 是一种选择性的 VEGFR2抑制剂,其 IC50=9 nM。
T22436 Takeda-6d

VEGFR Angiogenesis; Tyrosine Kinase/Adaptors
Takeda-6d 是一种新型、有效的 DFG-out RAF/血管内皮生长因子受体 2 (VEGFR2) 抑制剂,IC50 分别为 7.0 nM 和 2.2 nM。
T26852 BMS-605541

BMS605541,BMS 605541

VEGFR Angiogenesis; Tyrosine Kinase/Adaptors
BMS-605541 是一种有效的选择性血管内皮生长因子受体 2 (VEGFR-2) 激酶活性抑制剂 (Ki=49 nM) 。
T60396 JMS-053

Phosphatase Metabolism
JMS-053 是一种具有有效性和选择性的磷酸酶 DUSP3 抑制剂, 抑制 PTP4A3、 PTP4A1 、 PTP4A2 和 CDC25B,抑制癌细胞迁移和球体生长,避免血管内皮生长因子或脂多糖对微血管内皮屏障功能的破坏。
T2576 Brivanib (alaninate)

丙氨酸布立尼布,BMS-582664,Brivanib Alaninate

VEGFR; FGFR; Autophagy Angiogenesis; Autophagy; Tyrosine Kinase/Adaptors
Brivanib Alaninate (BMS-582664) 是一种血管内皮生长因子受体 2 (VEGFR2) 抑制剂的丙氨酸盐,IC50值为 25 nM,具有潜在的抗肿瘤活性。它对 VEGFR1 和 FGFR1 适度抑制,对 VEGFR2 的选择性是对 PDGFRβ 的 240 倍。
T76866 Icrucumab

LY 3012212,IMC-18F1

VEGFR Angiogenesis; Tyrosine Kinase/Adaptors
Icrucumab ( IMC-18F1) 是一种人源化靶向血管内皮生长因子受体-1 的 IgG1 单克隆抗体。Icrucumab具有抗肿瘤活性,Icrucumab 具有研究转移性结肠癌。
T2160 Suramin Sodium Salt

苏拉明钠,BAY-205,Suramin hexasodium salt,苏拉明钠盐,NF-060

Apoptosis; Phosphatase; SARS-CoV; Sirtuin; Reverse Transcriptase; Topoisomerase; Parasite Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
Suramin Sodium Salt (BAY-205) 是可逆的竞争性蛋白酪氨酸磷酸酶抑制剂。它抑制 IP5K,是抗寄生虫,抗肿瘤和抗血管生成剂。它是sirtuins 的有效抑制剂,也是 SARS-CoV-2 RNA 依赖性 RNA 聚合酶抑制剂。
T9473 4SC-203

FLT Angiogenesis; Tyrosine Kinase/Adaptors
4SC-203 是一种具有潜在的抗肿瘤活性的多激酶抑制剂。它对 FLT3/STK1、 FLT3 的突变形式以及 VEGFRs 具有选择性抑制作用。
T2064 Semaxinib

司马沙尼,SU5416

VEGFR Angiogenesis; Tyrosine Kinase/Adaptors
Semaxinib (SU5416) 是一种选择性的 VEGFR(Flk-1/KDR) 抑制剂,其 IC50=1.23 μM。
T68455 AP23846

AP-23846

Src Angiogenesis; Tyrosine Kinase/Adaptors
AP23846 是一种新型高效的 Src 家族激酶抑制剂,可降低人实体瘤细胞系中血管内皮生长因子和白细胞介素-8 的表达,并消除下游血管生成过程。
T6517 Golvatinib

E-7050,戈伐替尼

VEGFR; c-Met/HGFR Angiogenesis; Tyrosine Kinase/Adaptors
Golvatinib (E-7050) 是一种 c-Met (IC50:14 nM) 和 VEGFR2 (IC50:16 nM) 的双重抑制剂。
T3211 Midostaurin

米哚妥林,N-Benzoylstaurosporine,PKC412,CGP41231,CGP 41251,苯甲酰基十字孢碱

Others; PKC Chromatin/Epigenetic; Cytoskeletal Signaling; Others
Midostaurin (PKC412) 是一种多靶点蛋白激酶抑制剂,有抗肿瘤活性,对 PKCα/β/γ、Syk、Flk-1、Akt、PKA、c-Kit、c-Fgr、c-Src、FLT3、PDFRβ和VEGFR1/2的IC50值范围为 22 到500 nM 之间。
T33701 NM-3

NM-3,isocoumarin,NM 3,Isocoumarin NM-3,NM3

Apoptosis; Reactive Oxygen Species Apoptosis; Immunology/Inflammation; Metabolism; NF-κB
NM-3 是一种可口服的抗血管生成的抑制剂,具有抗肿瘤活性。NM-3在体外和体内可当作辐射调节剂使用。NM-3抑制血管内皮生长因子(VEGF),从而抑制内皮细胞的增殖。NM-3与活性氧的机制诱导细胞凋亡有关。
T9659 LCB 03-0110

3-(2-(3-(Morpholinomethyl)phenyl)thieno[3,2-b]pyridin-7-ylamino)phenol

Discoidin Domain Receptor (DDR) Tyrosine Kinase/Adaptors
LCB 03-0110 (3-(2-(3-(Morpholinomethyl)phenyl)thieno[3,2-b]pyridin-7-ylamino)phenol) 是一种盘状结构域受体家族酪氨酸激酶的强效抑制剂,可强烈抑制多种酪氨酸激酶,包括 c-Src 家族、脾酪氨酸激酶、布鲁顿酪氨酸激酶和血管内皮生长因子受体 2,它们对免疫很重要细胞信号传导和炎症反应。
T9928 Ranibizumab

VEGFR Angiogenesis; Tyrosine Kinase/Adaptors
Ranibizumab 是一种人源化单克隆抗体片段,旨在靶向和抑制血管内皮生长因子 (VEGF),包括 VEGF110、VEGF121 和 VEGF165。 Ranibizumab 选择性靶向和中和 VEGF-A 同工型的能力使其成为湿性年龄相关性黄斑变性 (AMD) 研究和治疗策略的重要组成部分。
T19710 Ciglitazone

Ciglitazona,U 63287,ADD3878,ADD-3878,U-63287,ADD 3878

Apoptosis; p38 MAPK; PPAR Apoptosis; DNA Damage/DNA Repair; MAPK; Metabolism
Ciglitazone (ADD 3878) 是一种强效和选择性的PPARγ激动剂(EC50:3μM)和口服降糖药。Ciglitazone 抑制th17细胞的增殖和分化,降低胰岛素水平、血管内皮生长因子的产生和血压,诱导胃癌细胞的细胞周期停止。Ciglitazone 能诱导负鼠肾上皮细胞的凋亡,激活p38 MAPK 和凋亡诱导因子(AIF)的核转位。 Ciglitazone 在肥胖症和高血糖症的动物模型中表现出降血糖活性。
T2283 PX-12

2-[(1-甲基丙基)二硫代]-1H-咪唑,IV-2,PX12

Thioredoxin Metabolism
PX-12 (PX12) 是一种可逆的硫氧还蛋白-1(Trx-1)抑制剂,能够抑制 MCF-7 细胞(IC50:1.9 μM)和HT-29 细胞(IC50:2.9 μM)的生长。
T16344 NS-2028

Others; Guanylate cyclase GPCR/G Protein; Others
NS-2028 是一种高度选择性的可溶性鸟苷酸环化酶抑制剂。它抑制 3-吗啉代-sydnonimine 在人培养的脐静脉内皮细胞中形成环状 GMP,IC50为30mM。它抑制小鼠小脑匀浆和神经元 NO 合酶中的可溶性鸟苷酸环化酶活性,IC50分别为 17 和 20 mM。它可降低血管内皮生长因子诱导的血管生成和通透性。
T28760 Setafrastat

Setafrastat is a vascular endothelial growth factor (VEGF) promotor and rotamase inhibitor.
T68526 VEGFR-IN-V

VEGFR-IN-V is a potent, vascular endothelial growth factor receptor-​2 (VEGFR-2) tyrosine kinase inhibitor.
T69487 ZK-261557

ZK-261557 is a new oral antiangiogenic molecule that inhibits all known vascular endothelial growth factor receptors. Vatalanib is under investigation for the treatment of solid tumors.
T2500L Cediranib maleate

AZD-2171,Recentin,西地尼布马来酸盐,AZD2171,AZD2171 maleate,AZD 2171

Cediranib is a potent and selective inhibitor of VEGF with antineoplastic activities. It inhibits all three vascular endothelial growth factor receptor (VEGF-1,-2,-3) tyrosine kinases, thereby blocking VEGF-signaling, angiogenesis, and tumor cell growth.
T1656L Vandetanib Fumarate

HSDB 8198,Zactima,Caprelsa,ZD 6474,Vandetanib

Vandetanib Fumarate is an orally available tyrosine kinase inhibitor. Vandetanib Fumarate works by blocking RET (REarranged during Transfection), vascular endothelial growth factor receptor (VEGFR-2, VEGFR-3), and epidermal growth factor receptor and to a
T68935 BMS-645737

BMS-645737 is an inhibitor of vascular endothelial growth factor (VEGF) receptor-2 and fibroblast growth factor (FGF) receptor-1. BMS-646737 has anti-angiogenic activity and was evaluated in nonclinical studies as a treatment for cancer.
T69209 ZK-304709

ZK-304709 is a potent multi-target tumor growth inhibitor with IC50 = nanomolar inhibitory activity to cyclin-dependent kinases 1, 2, 4, 7 and 9, as well as vascular endothelial growth factor receptor tyrosine kinase 1-3 and of platelet-derived growth factor receptor beta tyrosine kinase.
T74422 Sozinibercept

Sozinibercept (OPT 302; VGX-300) 是VEGFR-3的可溶性形式,能有效抑制血管生成原因子VEGF-C/D 的活性,抑制血管生成和血管渗漏。Sozinibercept 对大鼠糖尿病视网膜水肿也有抑制作用。
T37079 VEGFR2 Kinase Inhibitor II

Vascular endothelial growth factor receptor 2 (VEGFR2, also known as KDR and FLK1) is a receptor tyrosine kinase that regulates angiogenesis, vascular development, and embryonic hematopoiesis in response to VEGF isoforms A, C, and D. VEGFR2 kinase inhibitor II is a reversible, cell-permeable inhibitor of VEGFR2's kinase activity (IC50 = 70 nM). It less potently inhibits the platelet-derived growth factor receptor β (PDGFRβ; IC50 = 920 nM) and related receptor and non-receptor tyrosine kinases. V...
T61542 VEGFR-2-IN-17

VEGFR-2-IN-17 (Compound 15a) is a highly potent inhibitor of Vascular Endothelial Growth Factor Receptor 2 (VEGFR-2), with an IC50 value of 67.25 nM. This compound exhibits significant antitumor properties [1].
T71576 SIM010603

SIM010603 is a structurally novel, oral, multi-targeted receptor tyrosine kinase inhibitor. SIM010603 inhibited stem cell factor receptor (Kit), vascular endothelial growth factor receptor-2 (VEGFR-2), platelet-derived growth factor receptor-β (PDGFR-β), glial cell line-derived neurotrophic factor receptor (Rearranged during Transfection; RET), and Fms-like tyrosine kinase-3 (FLT3) with IC(50) values between 5.0 and 68.1 nmol/l. SIM010603 inhibited the phosphorylation of PDGFR-β and VEGFR-2. Mor...
T37595 Brain-Derived Acidic Fibroblast Growth Factor (1-11) (bovine) (trifluoroacetate salt)

Brain-derived acidic fibroblast growth factor (brain-derived aFGF) (1-11) is a peptide fragment of brain-derived aFGF. Brain-derived aFGF is an angiogenic vascular endothelial cell mitogen produced in bovine brain that has sequence homology to interleukin-1. aFGF (1-11) corresponds to amino acid residues 1-11 of the full length peptide.
T71187 Foretinib phosphate

Foretinib phosphate is an orally bioavailable small molecule with potential antineoplastic activity. MET/VEGFR2 inhibitor GSK1363089 binds to and selectively inhibits hepatocyte growth factor (HGF) receptor c-MET and vascular endothelial growth factor receptor 2 (VEGFR2), which may result in the inhibition of tumor angiogenesis, tumor cell proliferation and metastasis. The proto-oncogene c-MET has been found to be over-expressed in a variety of cancers.
T78253 Faricimab

RG7716

VEGFR Angiogenesis; Tyrosine Kinase/Adaptors
Faricimab是一种双特异性抗体,针对angiopoietin-2和血管内皮生长因子-A (VEGF-A)。该化合物可应用于糖尿病黄斑水肿(DME)的研究。
T69223 CC-1088

CC-1088 is an analog of thalidomide with potential antineoplastic activity that belongs to the functional class of agents called selective cytokine inhibitory drugs (SelCIDs). SelCIDs inhibit phosphodiesterase-4 (PDE 4), an enzyme involved in tumor necrosis factor alpha (TNF alpha) production. CC-1088 inhibits production of the cytokines vascular endothelial growth factor (VEGF) (a pro-angiogenic factor) and interleukin-6 (IL-6).
T80152 Protein LMWP

VEGFR Angiogenesis; Tyrosine Kinase/Adaptors
Protein LMWP为具有血管内皮生长因子(VEGF)抑制活性的细胞穿透肽,能够抑制肿瘤生长,适用于癌症研究领域。
T37819 Brain-Derived Acidic Fibroblast Growth Factor (102-111) (bovine) (trifluoroacetate salt)

Brain-derived acidic fibroblast growth factor (102-111) is a peptide fragment of brain-derived acidic fibroblast growth factor (aFGF). aFGF is an angiogenic vascular endothelial cell mitogen produced in bovine brain that has sequence homology to interleukin-1. It also shares sequence homology with the known neuropeptides neuromedin C , bombesin , neuromedin K , substance K , substance P , physalaemin, and eledoisin. aFGF (102-111) corresponds to amino acid residues 102-111 of the fulllength pept...
T71853 Enzastaurin HCl

Enzastaurin HCl, also known as DB-102 and LY317615, is a synthetic macrocyclic bisindolemaleimide with potential antineoplastic activity. Binding to the ATP-binding site, Enzastaurin HCl selectively inhibits protein kinase C beta, an enzyme involved in the induction of vascular endothelial growth factor (VEGF)-stimulated neo-angiogenesis. This agent may decrease tumor blood supply and so tumor burden.
T69354 Enzastaurin 2HCl

Enzastaurin 2HCl, also known as DB-102 and LY317615, is a synthetic macrocyclic bisindolemaleimide with potential antineoplastic activity. Binding to the ATP-binding site, Enzastaurin 2HCl selectively inhibits protein kinase C beta, an enzyme involved in the induction of vascular endothelial growth factor (VEGF)-stimulated neo-angiogenesis. This agent may decrease tumor blood supply and so tumor burden.
T70903 KRH102053

KRH102053 is a HIF-1alpha inhibitor. KRH102053 decreased the protein level of HIF-1alpha and the mRNA levels of HIF-regulated downstream target genes, such as vascular endothelial growth factor, aldolase A, enolase 1 and monocarboxylate transporter 4. Consistent with these results, KRH102053 also inhibited the rates of HIF-related migration and invasion of HOS cells as well as the degree of tube formation in human umbilical vein endothelium cells.
T68546 PF-00337210

PF-00337210 is an orally available ATP-competitive inhibitor of the vascular endothelial growth factor receptor type 2 (VEGFR2), with potential anti-angiogenesis and antineoplastic activities. Upon administration, the VEGFR2 tyrosine kinase inhibitor PF-00337210 selectively binds to VEGFR2 and prevents its phosphorylation which may result in an inhibition of migration, proliferation and survival of endothelial cells, microvessel formation, the inhibition of tumor cell proliferation, and may even...
T34811 Terrein

NSC 291308,土曲霉酮,Terrain,(+)Terrein,NSC291308,NSC-291308

Terrain, also known as NSC 291308, is a fungal metabolite with diverse biological activities. Terrein reduces age-related inflammation induced by oxidative stress through Nrf2/ERK1/2/HO-1 signalling in aged HDF cells. (+)-terrein suppresses interleukin-6/
T75156L Bevasiranib sodium

Bevasiranib sodium 是一种siRNA,可沉默产生血管内皮生长因子(VEGF)的基因。VEGF 在脉络膜新生血管形成(choroidal neo-vascularization, CNV)的发病机制中起着关键作用,而CNV 是湿性年龄相关性黄斑变性(wet age-related macular degeneration, wet AMD)的前兆。
T75156 Bevasiranib

Bevasiranib 是一种siRNA,可沉默产生血管内皮生长因子(VEGF)的基因。VEGF 在脉络膜新生血管形成(choroidal neo-vascularization, CNV)的发病机制中起着关键作用,而CNV 是湿性年龄相关性黄斑变性(wet age-related macular degeneration, wet AMD)的前兆。
T71180 Oglufanide disodium

Oglufanide disodium is t he disodium salt of a synthetic form of a naturally-occurring dipeptide consisting of L-glutamic acid and L-tryptophan with potential antiangiogenic and potential immunomodulating activities. Oglufanide inhibits vascular endothelial growth factor (VEGF), which may inhibit angiogenesis. This agent has also been reported to stimulate the immune response to hepatitic C virus and intracellular bacterial infections. Check for active clinical trials or closed clinical trials u...
T36550 CAY10535

TPα and TPβ are two isoforms of the human TP receptor, the G protein-coupled receptor (GPCR) that mediates the actions of thromboxane A2 (TXA2). Although their distinct physiological functions have not been fully elucidated, TPβ is believed to be responsible for vascular endothelial growth factor-induced endothelial cell differentiation and migration whereas TPα appears to be the predominant isoform expressed in platelets. CAY10535 is a TP receptor antagonist that shows ~20-fold selectivity for ...
T68511 KRH102140

KRH102140 is a potent activator of PHD2. KRH102140, which has a structure similar to KRH102053. KRH102140 more efficiently suppressed HIF-1α than KRH102053 in human osteosarcoma cells under hypoxia. Furthermore, KRH102140 decreased the mRNA levels of HIF-regulated downstream target genes associated with angiogenesis and energy metabolism such as vascular endothelial growth factor, adrenomedullin, Glut1, aldolase A, enolase 1 and monocarboxylate transporter 4. KRH102140 also inhibited tube format...

化合物

hVEGF-IN-1
Cat.No: T4288
Synonym:
Target: VEGFR
Naphazoline
Cat.No: T21445
Synonym: AK-Con,Naphcon-a,Clear Eyes,All Clear,萘甲唑林
Target: Adrenergic Receptor
Tyrphostin A9
Cat.No: T2479
Synonym: Malonoben,Tyrphostin 9,SF 6847,AG 17,RG-50872
Target: EGFR, VEGFR, Influenza Virus, PDGFR
ZD-4190
Cat.No: T5475
Synonym:
Target: EGFR, VEGFR
SU5208
Cat.No: T22432
Synonym: 3-[(Thien-2-yl)methylene]-2-indolinone
Target: VEGFR
NVP-BAW2881
Cat.No: T3641
Synonym: BAW2881
Target: Raf, VEGFR, Bcr-Abl
Takeda-6d
Cat.No: T22436
Synonym:
Target: VEGFR
BMS-605541
Cat.No: T26852
Synonym: BMS605541,BMS 605541
Target: VEGFR
JMS-053
Cat.No: T60396
Synonym:
Target: Phosphatase
Brivanib (alaninate)
Cat.No: T2576
Synonym: 丙氨酸布立尼布,BMS-582664,Brivanib Alaninate
Target: VEGFR, FGFR, Autophagy
Icrucumab
Cat.No: T76866
Synonym: LY 3012212,IMC-18F1
Target: VEGFR
Suramin Sodium Salt
Cat.No: T2160
Synonym: 苏拉明钠,BAY-205,Suramin hexasodium salt,苏拉明钠盐,NF-060
Target: Apoptosis, Phosphatase, SARS-CoV, Sirtuin, Reverse Transcriptase, Topoisomerase, Parasite
4SC-203
Cat.No: T9473
Synonym:
Target: FLT
Semaxinib
Cat.No: T2064
Synonym: 司马沙尼,SU5416
Target: VEGFR
AP23846
Cat.No: T68455
Synonym: AP-23846
Target: Src
Golvatinib
Cat.No: T6517
Synonym: E-7050,戈伐替尼
Target: VEGFR, c-Met/HGFR
Midostaurin
Cat.No: T3211
Synonym: 米哚妥林,N-Benzoylstaurosporine,PKC412,CGP41231,CGP 41251,苯甲酰基十字孢碱
Target: Others, PKC
NM-3
Cat.No: T33701
Synonym: NM-3,isocoumarin,NM 3,Isocoumarin NM-3,NM3
Target: Apoptosis, Reactive Oxygen Species
LCB 03-0110
Cat.No: T9659
Synonym: 3-(2-(3-(Morpholinomethyl)phenyl)thieno[3,2-b]pyridin-7-ylamino)phenol
Target: Discoidin Domain Receptor (DDR)
Ranibizumab
Cat.No: T9928
Synonym:
Target: VEGFR
Ciglitazone
Cat.No: T19710
Synonym: Ciglitazona,U 63287,ADD3878,ADD-3878,U-63287,ADD 3878
Target: Apoptosis, p38 MAPK, PPAR
PX-12
Cat.No: T2283
Synonym: 2-[(1-甲基丙基)二硫代]-1H-咪唑,IV-2,PX12
Target: Thioredoxin
NS-2028
Cat.No: T16344
Synonym:
Target: Others, Guanylate cyclase
Setafrastat
Cat.No: T28760
Synonym:
Target:
VEGFR-IN-V
Cat.No: T68526
Synonym:
Target:
ZK-261557
Cat.No: T69487
Synonym:
Target:
Cediranib maleate
Cat.No: T2500L
Synonym: AZD-2171,Recentin,西地尼布马来酸盐,AZD2171,AZD2171 maleate,AZD 2171
Target:
Vandetanib Fumarate
Cat.No: T1656L
Synonym: HSDB 8198,Zactima,Caprelsa,ZD 6474,Vandetanib
Target:
BMS-645737
Cat.No: T68935
Synonym:
Target:
ZK-304709
Cat.No: T69209
Synonym:
Target:
Sozinibercept
Cat.No: T74422
Synonym:
Target:
VEGFR2 Kinase Inhibitor II
Cat.No: T37079
Synonym:
Target:
VEGFR-2-IN-17
Cat.No: T61542
Synonym:
Target:
SIM010603
Cat.No: T71576
Synonym:
Target:
Brain-Derived Acidic Fibroblast Growth Factor (1-11) (bovine) (trifluoroacetate salt)
Cat.No: T37595
Synonym:
Target:
Foretinib phosphate
Cat.No: T71187
Synonym:
Target:
Faricimab
Cat.No: T78253
Synonym: RG7716
Target: VEGFR
CC-1088
Cat.No: T69223
Synonym:
Target:
Protein LMWP
Cat.No: T80152
Synonym:
Target: VEGFR
Brain-Derived Acidic Fibroblast Growth Factor (102-111) (bovine) (trifluoroacetate salt)
Cat.No: T37819
Synonym:
Target:
Enzastaurin HCl
Cat.No: T71853
Synonym:
Target:
Enzastaurin 2HCl
Cat.No: T69354
Synonym:
Target:
KRH102053
Cat.No: T70903
Synonym:
Target:
PF-00337210
Cat.No: T68546
Synonym:
Target:
Terrein
Cat.No: T34811
Synonym: NSC 291308,土曲霉酮,Terrain,(+)Terrein,NSC291308,NSC-291308
Target:
Bevasiranib sodium
Cat.No: T75156L
Synonym:
Target:
Bevasiranib
Cat.No: T75156
Synonym:
Target:
Oglufanide disodium
Cat.No: T71180
Synonym:
Target:
CAY10535
Cat.No: T36550
Synonym:
Target:
KRH102140
Cat.No: T68511
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
TWA2417 Sodium taurocholate

牛黄胆酸钠(牛胆酸钠,牛胆酸钠盐,牛磺膽酸鈉,牛磺胆酸钠,牛磺胆酸钠盐,牛胆酸钠水合物,水合牛磺胆酸钠,牛胆酸钠(混合物),牛黄胆酸钠(水合),牛磺胆酸钠(标准品)),Taurocholate Sodium

Others Others
Sodium taurocholate (Taurocholate Sodium) hydrate 具有显著的生物学效应,例如通过上调 VEGF-A 的表达抑制肝动脉结扎所致的胆道损伤。对免疫系统具有一定的调节作用。
T7203 Oglufanide

奥谷法奈,L-Glutamyl-L-tryptophan,H-Glu-Trp-OH

VEGFR; HCV Protease; Endogenous Metabolite Angiogenesis; Metabolism; Microbiology/Virology; Proteases/Proteasome; Tyrosine Kinase/Adaptors
Oglufanide (H-Glu-Trp-OH) 是一种从小牛胸腺中分离出来的二肽免疫调节剂,可抑制血管内皮生长因子,可刺激细胞内细菌感染和对丙型肝炎病毒的免疫反应。
TN5942 Dammarenediol II

达玛烯二醇II,Dammar-24-ene-3,20-diol

Dammarenediol II may have the ability to prevent diabetic microvascular complications, including diabetic retinopathy, it can inhibit vascular endothelial growth factor (VEGF)-induced intracellular reactive oxygen species generation and stress fiber forma
T38250 L-Sepiapterin

L-Sepiapterin, also known as Sepiapterin, is a precursor compound crucial for the production of tetrahydrobiopterin (BH4), which serves as a coenzyme for endothelial nitric oxide synthase (eNOS). This compound demonstrates its efficacy by improving endothelial dysfunction in small mesenteric arteries from db/db mice and promoting angiogenesis. Moreover, L-Sepiapterin exerts inhibitory effects on cellular proliferation and migration in ovarian cancer cells through the down-regulation of p70S6K-de...

天然产物

Sodium taurocholate
Cat.No: TWA2417
Synonym: 牛黄胆酸钠(牛胆酸钠,牛胆酸钠盐,牛磺膽酸鈉,牛磺胆酸钠,牛磺胆酸钠盐,牛胆酸钠水合物,水合牛磺胆酸钠,牛胆酸钠(混合物),牛黄胆酸钠(水合),牛磺胆酸钠(标准品)),Taurocholate Sodium
Target: Others
Oglufanide
Cat.No: T7203
Synonym: 奥谷法奈,L-Glutamyl-L-tryptophan,H-Glu-Trp-OH
Target: VEGFR, HCV Protease, Endogenous Metabolite
Dammarenediol II
Cat.No: TN5942
Synonym: 达玛烯二醇II,Dammar-24-ene-3,20-diol
Target:
L-Sepiapterin
Cat.No: T38250
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPY-02432 VEGF164 Protein, Rat, Recombinant

血管内皮生长因子,vascular endotheli

Rat Baculovirus Insect Cells
VEGF164 Protein, Rat, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 19.2 kDa and the accession number is P16612-2.
TMPY-04911 VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated

vascular endothelial...

Human,Cynomolgus HEK293 Cells
VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 23.1 kDa and the accession number is P15692-4.
TMPY-01717 VEGF164 Protein, Mouse, Recombinant

vascular endothelial...

Mouse Baculovirus Insect Cells
VEGF164 Protein, Mouse, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 19.4 kDa and the accession number is Q00731-2.
TMPJ-00865 VEGF121 Protein, Human, Recombinant (His)

VEGFA,VEGF-A,Vascula...

Human HEK293 Cells
Human VEGF121, also known as Vascular endothelial growth factor A, VEGFA, Vascular permeability factor, VPF and VEGF, is a homodimeric, heparin-binding glycoprotein which belongs to the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family. VEGF-A is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis, permeabilization of blood vessel...
TMPY-03698 VEGF121b Protein, Human, Recombinant

MVCD1,VEGF,VPF,vascular endot...

Human HEK293 Cells
VEGF121b Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 34.10 kDa and the accession number is P15692-9.
TMPY-03705 VEGF164 Protein, Canine, Recombinant

血管内皮生长因子,vascular endotheli

Canine HEK293 Cells
VEGF164 Protein, Canine, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 17 kDa and the accession number is Q9MYV3-3.
TMPY-03080 VEGF165 Protein, Danio rerio (zebrafish), Recombinant

血管内皮生长因子,vascular endotheli

Danio rerio (zebrafish) Baculovirus Insect Cells
VEGF165 Protein, Danio rerio (zebrafish), Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 19.2 kDa and the accession number is O73682.
TMPY-01656 VEGF183 Protein, Human, Recombinant

血管内皮生长因子,VEGF165,VPF,VEGF,vascular

Human Baculovirus Insect Cells
VEGF183 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 21 kDa and the accession number is P15692-3.
TMPY-05798 VEGF145 Protein, Human, Recombinant

血管内皮生长因子,vascular endotheli

Human HEK293 Cells
VEGF145 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 16.92 kDa and the accession number is P15692-6.
TMPK-00823 VEGF165 Protein, Human, Recombinant (His & Avi)

血管内皮生长因子,RP1-261G23.1,MVCD1,MGC70609,VEGFA,VEGFMGC7...

Human HEK293 Cells
Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189. VEGF165 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 22.2 kDa and the accession number is P15692-4.
TMPJ-00864 VEGF165 Protein, Human, Recombinant

Vascular Endothelial...

Human HEK293 Cells
Human Vascular endothelial growth factor (VEGF), also known as VEGF-A and vascular permeability factor (VPF), belongs to the platelet-derived growth factor family of cysteine-knot growth factors. It is a potent activator in vasculogenesis and angiogenesis both physiologically and pathologically. VEGF-A has 8 differently spliced isoforms, of which VEGF165 is the most abundant one. VEGF165 is a disulfide-linked homodimer consisting of two glycosylated 165 amino acid polypeptide chains. VEGF stimul...
TMPJ-00412 VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)

Vascular endothelial...

Human HEK293 Cells
Human Vascular endothelial growth factor receptor 1(VEGFR-1, FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 is widely expressed in human tissues including normal lung, placenta, liver, kidney, heart and brain tissues. It is specifically expressed in most of the vascular endothelial cellsand peripheral blood monocytes. VEGFR-1 contains seven Ig-like C2-type domains and one protein kinas...
TMPK-00825 VEGF121 Protein, Human, Recombinant (His & Avi)

VPF,VEGF,VEGFA,VEGFMGC70609,血管内皮生长因子,MGC70609,RP1-2...

Human HEK293 Cells
Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189. VEGF121 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 17 kDa and the accession number is P15692-9.
TMPK-00826 VEGF121 Protein, Human, Recombinant (His & Avi), Biotinylated

VAS,VEGFMGC70609,RP1-261G23.1,血管内皮生长因子,VEGFA

Human HEK293 Cells
Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189. VEGF121 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 17 kDa and the accession number is P15692-9.
TMPJ-00987 PLGF/PGF Protein, Mouse, Recombinant (His)

Plgf,PlGF-2,PGFL,PGF,SHGC-10760,D12S1900,Placent

Mouse HEK293 Cells
Placental growth factor is a protein that in humans is encoded by the PGF gene. It is a secreted protein and belongs to the PDGF/VEGF growth factor family. The protein is a member of the VEGF (vascular endothelial growth factor) sub-family-a key molecule in angiogenesis and vasculogenesis, in particular during embryogenesis. The main source of PGF during pregnancy is the placental trophoblast. PGF is also expressed in many other tissues, including the villous trophoblast.
TMPK-00822 VEGF165 Protein, Human, Recombinant (His & Avi), FITC-Labeled

RP1-261G23.1,VEGFA,MGC70609,VEGF,VEGFMGC70609,VPF,V...

Human HEK293 Cells
Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189. VEGF165 Protein, Human, Recombinant (His & Avi), FITC-Labeled is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 22.2 kDa and the accession number is P15692-4.
TMPK-00978 ECSCR Protein, Human, Recombinant (hFc)

ECSM2,ECSCR,ARIA

Human HEK293 Cells
Endothelial cell-specific chemotaxis receptor (ECSCR) is a cell surface protein expressed by blood endothelial cells with roles in endothelial cell migration and signal transduction. Zebrafish ecscr is expressed in angioblasts and in axial vessels during angioblast migration and vasculogenesis. Morpholino-directed ecscr knockdown resulted in defective angioblast migration in the posterior lateral plate mesoderm, a process known to depend on vascular endothelial-derived growth factor (VEGF). ECSC...
TMPK-01153 PLVAP Protein, Human, Recombinant (His)

PV1,FELS

Human HEK293 Cells
Plasmalemma vesicle-associated protein (PLVAP, also called PV-1) is the only protein that forms endothelial diaphragms. PLVAP expression is very low in the normal blood-retinal barrier; however, pathological factors such as high glucose and vascular endothelial growth factor (VEGF) induce its expression, leading to the exacerbation of cellular permeability. Because the new blood vessels are fragile and leaky, PLVAP could possibly be considered a therapeutic target against retinovascular diseases...
TMPK-00988 ECSCR Protein, Mouse, Recombinant (hFc)

ECSCR,ARIA,ECSM2

Mouse HEK293 Cells
Endothelial cell-specific chemotaxis receptor (ECSCR) is a cell surface protein expressed by blood endothelial cells with roles in endothelial cell migration and signal transduction. Zebrafish ecscr is expressed in angioblasts and in axial vessels during angioblast migration and vasculogenesis. Morpholino-directed ecscr knockdown resulted in defective angioblast migration in the posterior lateral plate mesoderm, a process known to depend on vascular endothelial-derived growth factor (VEGF). ECSC...
TMPJ-00361 Endoglin Protein, Human, Recombinant (Trx & His)

CD105,END,Endoglin,ENG

Human E. coli
Endoglin is a single-pass type I membrane protein which restricted to endothelial cells in all tissues except bone marrow. Endoglin as major glycoprotein of vascular endothelium, it has been found on endothelial cells, activated macrophages, fibroblasts, and smooth muscle cells. Furthermore, Homodimer forms a heteromeric complex with the signaling receptors for transforming growth factor-beta: TGFBR1 and/or TGFBR2. It may have an important role in the binding of endothelial cells to integrins an...
TMPK-01044 VEGFC Protein, Human, Recombinant (His & Avi), Biotinylated

血管内皮生长因子,Flt4-L,VRP,VEGF-C,VEGFC

Human HEK293 Cells
the lymphangiogenic factors vascular endothelial growth factor C (VEGFC) and VEGFD are cleaved by thrombin and plasmin, serine proteases generated during hemostasis and wound healing. Genetic studies reveal that platelet enhancement of lymphatic growth after wounding is dependent on the release of VEGFC, but not VEGFD, a finding consistent with high expression of VEGFC in both platelets and avian thrombocytes. VEGFC Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mam...
TMPK-01043 VEGFC Protein, Human, Recombinant (His & Avi)

Flt4-L,血管内皮生长因子,VEGFC,VRP,VEGF-C

Human HEK293 Cells
the lymphangiogenic factors vascular endothelial growth factor C (VEGFC) and VEGFD are cleaved by thrombin and plasmin, serine proteases generated during hemostasis and wound healing. Genetic studies reveal that platelet enhancement of lymphatic growth after wounding is dependent on the release of VEGFC, but not VEGFD, a finding consistent with high expression of VEGFC in both platelets and avian thrombocytes. VEGFC Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells w...
TMPK-00645 VEGFR2/KDR Protein, Rhesus macaque, Recombinant (His)

KRD1,VEGFR2,FLK1,CD309,Ly73,VEGFR,VEGFR-21,KDR

Rhesus HEK293 Cells
Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. The tyrosine kinase receptor vascular endothelial growth factor receptor 2 (VEGFR2) is a key regulator of angiogenesis. VEGFR2/KDR Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with ...
TMPY-04327 VEGFB Protein, Human, Recombinant (hFc)

VRF,血管内皮生长因子,vascular endothe...

Human HEK293 Cells
Vascular endothelial growth factor-B (VEGF-B) is closely related to VEGF-A, an effector of blood vessel growth during development and disease and a strong candidate for angiogenic therapies. In detail, VEGFB can positively prevent the Ang II-induced rising in the size of cardiomyocyte as well as reduce Ang II-induced mRNA and protein levels of β-MHC (β-myosin heavy chain), BNP (brain natriuretic peptide), and ANP (atrial natriuretic peptide). Moreover, VEGFB can regulate the decline of the Ang I...
TMPK-00454 VEGFR2/KDR Protein, Human, Recombinant (His & Avi)

VEGFR-21,Ly73,KRD1,VEGFR2,CD309,FLK1,VEGFR,KDR

Human HEK293 Cells
Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. The tyrosine kinase receptor vascular endothelial growth factor receptor 2 (VEGFR2) is a key regulator of angiogenesis. VEGFR2/KDR Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-H...
TMPJ-00054 PLGF-2 Protein, Human, Recombinant (His)

PlGF-2,PlGF2,PlGF,PGF,PGFL

Human HEK293 Cells
Placental growth factor is a protein that in humans is encoded by the PGF gene. It is a secreted protein and belongs to the PDGF/VEGF growth factor family. Alternate splicing results in at least three human mature PlGF forms containing 131 (PlGF‑1), 152 (PlGF‑2), and 203 (PlGF‑3) amino acids (aa) respectively. PlGF is mainly found as a variably glycosylated, secreted, 55 ‑ 60 kDa disulfide linked homodimer.The protein is a member of the VEGF (vascular endothelial growth factor) sub-family-a key ...
TMPJ-00330 GPC1 Protein, Human, Recombinant (His)

Glypican-1,GPC1

Human HEK293 Cells
The Glypicans are a small multigene family of GPI-linked proteoglycans that play a key role in growth factor signaling. Human Glypican 1 (GPC1) is synthesized as a 558 amino acid (aa) preproprecursor that contains a 23 aa signal sequence, a 507 aa mature segment, and a 28 aa C-terminal prosegment. There are two potential N-linked and four potential O-linked sites for glycosylation or glycanation. There are potentially two heparan sulfate (HS) modifications on GPC1 that could contribute to a nati...
TMPY-04468 STK16 Protein, Human, Recombinant (His & NusA)

MPSK,serine/threonine kinase 16,TSF1,KRCT,PKL12

Human E. coli
Serine/threonine-protein kinase 16, also known as myristoylated and palmitoylated serine/threonine-protein kinase, Protein kinase PKL12, TGF-beta-stimulated factor 1, TSF-1, MPSK1 and STK16, is a membrane protein that is ubiquitously expressed at very low levels. STK16 / MPSK1 belongs to the protein kinase superfamily and Ser/Thr protein kinase family. It contains one protein kinase domain. Transforming growth factor-beta (TGF-beta) shows a variety of biological activities in various organs or c...
TMPY-01709 HIF-1 alpha Protein, Human, Recombinant (His)

bHLHe78,HIF-1 α,hypoxia inducible fact...

Human E. coli
HIF-1 alpha, also known as HIF1A, contains 1 basic helix-loop-helix (bHLH) domain, 1 PAC (PAS-associated C-terminal) domain, and 2 PAS (PER-ARNT-SIM) domains. It is one of the two subunits of Hypoxia-inducible factor-1 (HIF1). HIF1 is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has...
TMPK-01419 Peptide Ready HLA-A*03:01&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated

MHC,HLA-A*02:01,Peptide Ready

Human HEK293 Cells
Peptide Ready HLA-A*03:01&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-A*03:01. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can be readily tetramerized and loaded with peptides of choice in a high-throughput manner.
TMPK-01426 Peptide Ready HLA-A*11:01&B2M Monomer Protein, Human, MHC (His & Avi)

HLA-A*02:01,Peptide Ready,MHC

Human HEK293 Cells
Peptide Ready HLA-A*11:01&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-A*11:01. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can be readily tetramerized and loaded with peptides of choice in a high-throughput manner.
TMPK-01421 Peptide Ready HLA-A*02:01&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated

HLA-A*02:01,MHC,Peptide Ready

Human HEK293 Cells
HLA-A*02:01&B2M&Peptide ready Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-A*02:01. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can be readily tetramerized and loaded with peptides of choice in a high-throughput manner.
TMPK-01420 Peptide Ready HLA-A*03:01&B2M Monomer Protein, Human, MHC (His & Avi)

Peptide Ready,MHC,HLA-A*02:01

Human HEK293 Cells
Peptide Ready HLA-A*03:01&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-A*03:01. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can be readily tetramerized and loaded with peptides of choice in a high-throughput manner.
TMPK-01422 Peptide Ready HLA-A*02:01&B2M Monomer Protein, Human, MHC (His & Avi)

Peptide Ready,MHC,HLA-A*02:01

Human HEK293 Cells
Peptide Ready HLA-A*02:01&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-A*02:01. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can be readily tetramerized and loaded with peptides of choice in a high-throughput manner.
TMPK-01425 Peptide Ready HLA-A*11:01&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated

MHC,HLA-A*02:01,Peptide Ready

Human HEK293 Cells
Peptide Ready HLA-A*11:01&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-A*11:01. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can be readily tetramerized and loaded with peptides of choice in a high-throughput manner.
TMPK-01410 Peptide Ready HLA-A*24:02&B2M Monomer Protein, Human, MHC (His & Avi)

HLA-A,MHC,Peptide Ready

Human HEK293 Cells
Peptide Ready HLA-G&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-G. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can be readily tetramerized and loaded with peptides of choice in a high-throughput manner.
TMPK-01409 Peptide Ready HLA-A*24:02&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated

Peptide Ready,MHC,HLA-A

Human HEK293 Cells
Peptide Ready HLA-G&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-G. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can be readily tetramerized and loaded with peptides of choice in a high-throughput manner.
TMPK-01415 APC-equivalent Peptide Ready HLA-A*02:01&B2M Tetramer Protein, Human, MHC (His)

Peptide Ready,HLA-A*02:01,MHC

Human HEK293 Cells
Peptide Ready HLA-A*02:01&B2M Tetramer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-A*02:01. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can be readily tetramerized and loaded with peptides of choice in a high-throughput manner.
TMPK-01408 HLA-A*02:01&B2M&KRAS G12V (KLVVVGAVGV) Monomer Protein, Human, MHC (His & Avi), Biotinylated

RALD,KRAS1,KRAS2,K-RAS2B...

Human E. coli
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01401 HLA-A*11:01&B2M&KRAS WT (VVVGAGGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi)

MHC,CFC2,K-Ras 2,RALD,K-RAS4A...

Human E. coli
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target.
TMPK-01429 HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi), Biotinylated

MHC,K-Ras 2,NS,K-RAS4A,KRA

Human E. coli
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01449 HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Monomer Protein, Human, MHC (E. coli, His & Avi)

MHC,CT6.1,CTAG1,LAGE-2,MY-ESO-1,NY-ESO-1,E...

Human E. coli
NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy.
TMPK-01529 HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Monomer Protein, Human, MHC (His & Avi)

K-RAS4A,KRAS1,MHC,K-RAS2...

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01455 HLA-A*02:01&B2M&PRAME (SLLQHLIGL) Monomer Protein, Human, MHC (His & Avi)

OIP4,PRAME,OIP-4,MAPE

Human HEK293 Cells
PRAME (PReferentially expressed Antigen in MElanoma) is a melanoma-associated antigen expressed in cutaneous and ocular melanomas and some other malignant neoplasms, while its expression in normal tissue and benign tumors is limited.
TMPK-01473 HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Monomer Protein, Human, MHC (His & Avi), Biotinylated

CT1.3,MAGE-3,MZ2-D,MZ2D,HLA-A2402...

Human HEK293 Cells
Melanoma antigen gene A3 (MAGE-A3) is one of the most immunogenic cancer testis antigens and is common in various types of cancers. MAGE-A3 can be considered as a predictor for poor prognosis and an option for vaccine immunotherapy in patients with PCa.
TMPK-01488 HLA-A*11:01&B2M&KRAS WT (VVVGAGGVGK) Monomer Protein, Human, MHC (His & Avi)

K-RAS4A,MHC,GTPase Kras,...

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target.
TMPK-01445 HLA-A*02:01&B2M&MAGE-A1 (KVLEYVIKV) Monomer Protein, Human, MHC (His & Avi), Biotinylated

CT1.1,MAGE1,MAGE-1,MAGE-A

Human HEK293 Cells
MAGE-A1 belongs to the chromosome X-clustered genes of cancer-testis antigen family and is normally expressed in the human germ line but is also overexpressed in various tumors.
TMPK-01458 HLA-A*11:01&B2M&KRAS G12A (VVVGAAGVGK) Monomer Protein, Human, MHC (His & Avi)

K-Ras 2,GTPase Kras,KRAS...

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01463 HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Monomer Protein, Human, MHC (His & Avi)

C-K-RAS,KI-RAS,KRAS1,K-RA

Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01477 HLA-A*02:01&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi), Biotinylated

HPAFP,FETA,Alpha-1-fetop...

Human HEK293 Cells
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
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重组蛋白

VEGF164 Protein, Rat, Recombinant
Cat.No: TMPY-02432
Species: Rat
Expression System: Baculovirus Insect Cells
VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-04911
Species: Human,Cynomolgus
Expression System: HEK293 Cells
VEGF164 Protein, Mouse, Recombinant
Cat.No: TMPY-01717
Species: Mouse
Expression System: Baculovirus Insect Cells
VEGF121 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00865
Species: Human
Expression System: HEK293 Cells
VEGF121b Protein, Human, Recombinant
Cat.No: TMPY-03698
Species: Human
Expression System: HEK293 Cells
VEGF164 Protein, Canine, Recombinant
Cat.No: TMPY-03705
Species: Canine
Expression System: HEK293 Cells
VEGF165 Protein, Danio rerio (zebrafish), Recombinant
Cat.No: TMPY-03080
Species: Danio rerio (zebrafish)
Expression System: Baculovirus Insect Cells
VEGF183 Protein, Human, Recombinant
Cat.No: TMPY-01656
Species: Human
Expression System: Baculovirus Insect Cells
VEGF145 Protein, Human, Recombinant
Cat.No: TMPY-05798
Species: Human
Expression System: HEK293 Cells
VEGF165 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00823
Species: Human
Expression System: HEK293 Cells
VEGF165 Protein, Human, Recombinant
Cat.No: TMPJ-00864
Species: Human
Expression System: HEK293 Cells
VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00412
Species: Human
Expression System: HEK293 Cells
VEGF121 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00825
Species: Human
Expression System: HEK293 Cells
VEGF121 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00826
Species: Human
Expression System: HEK293 Cells
PLGF/PGF Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00987
Species: Mouse
Expression System: HEK293 Cells
VEGF165 Protein, Human, Recombinant (His & Avi), FITC-Labeled
Cat.No: TMPK-00822
Species: Human
Expression System: HEK293 Cells
ECSCR Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00978
Species: Human
Expression System: HEK293 Cells
PLVAP Protein, Human, Recombinant (His)
Cat.No: TMPK-01153
Species: Human
Expression System: HEK293 Cells
ECSCR Protein, Mouse, Recombinant (hFc)
Cat.No: TMPK-00988
Species: Mouse
Expression System: HEK293 Cells
Endoglin Protein, Human, Recombinant (Trx & His)
Cat.No: TMPJ-00361
Species: Human
Expression System: E. coli
VEGFC Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-01044
Species: Human
Expression System: HEK293 Cells
VEGFC Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-01043
Species: Human
Expression System: HEK293 Cells
VEGFR2/KDR Protein, Rhesus macaque, Recombinant (His)
Cat.No: TMPK-00645
Species: Rhesus
Expression System: HEK293 Cells
VEGFB Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04327
Species: Human
Expression System: HEK293 Cells
VEGFR2/KDR Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00454
Species: Human
Expression System: HEK293 Cells
PLGF-2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00054
Species: Human
Expression System: HEK293 Cells
GPC1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00330
Species: Human
Expression System: HEK293 Cells
STK16 Protein, Human, Recombinant (His & NusA)
Cat.No: TMPY-04468
Species: Human
Expression System: E. coli
HIF-1 alpha Protein, Human, Recombinant (His)
Cat.No: TMPY-01709
Species: Human
Expression System: E. coli
Peptide Ready HLA-A*03:01&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01419
Species: Human
Expression System: HEK293 Cells
Peptide Ready HLA-A*11:01&B2M Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01426
Species: Human
Expression System: HEK293 Cells
Peptide Ready HLA-A*02:01&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01421
Species: Human
Expression System: HEK293 Cells
Peptide Ready HLA-A*03:01&B2M Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01420
Species: Human
Expression System: HEK293 Cells
Peptide Ready HLA-A*02:01&B2M Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01422
Species: Human
Expression System: HEK293 Cells
Peptide Ready HLA-A*11:01&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01425
Species: Human
Expression System: HEK293 Cells
Peptide Ready HLA-A*24:02&B2M Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01410
Species: Human
Expression System: HEK293 Cells
Peptide Ready HLA-A*24:02&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01409
Species: Human
Expression System: HEK293 Cells
APC-equivalent Peptide Ready HLA-A*02:01&B2M Tetramer Protein, Human, MHC (His)
Cat.No: TMPK-01415
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&KRAS G12V (KLVVVGAVGV) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01408
Species: Human
Expression System: E. coli
HLA-A*11:01&B2M&KRAS WT (VVVGAGGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi)
Cat.No: TMPK-01401
Species: Human
Expression System: E. coli
HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi), Biotinylated
Cat.No: TMPK-01429
Species: Human
Expression System: E. coli
HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Monomer Protein, Human, MHC (E. coli, His & Avi)
Cat.No: TMPK-01449
Species: Human
Expression System: E. coli
HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01529
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&PRAME (SLLQHLIGL) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01455
Species: Human
Expression System: HEK293 Cells
HLA-A*24:02&B2M&MAGE-A3 (IMPKAGLLI) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01473
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&KRAS WT (VVVGAGGVGK) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01488
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&MAGE-A1 (KVLEYVIKV) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01445
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&KRAS G12A (VVVGAAGVGK) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01458
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01463
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01477
Species: Human
Expression System: HEK293 Cells
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